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- Title
Tolerability profiles of leukotriene receptor antagonists and long-acting beta2-adrenoceptor agonists in combination with inhaled corticosteroids for treatment of asthma: a review.
- Authors
Colucci, R; Fornai, M; Tuccori, M; Antonioli, L; Pasqualetti, G; Blandizzi, C; Del Tacca, M
- Abstract
Inhaled corticosteroids, long-acting beta2-adrenoceptor agonists, and leukotriene receptor antagonists are widely used for treatment of asthma. Inhaled corticosteroids are recommended as first-line therapy, whereas long-acting beta2-adrenoceptor agonists and leukotriene receptor antagonists are indicated as add-on therapy in patients not adequately controlled with corticosteroids alone. A number of studies have investigated the efficacy of combinations of these drugs in asthma, but several issues concerning the safety of these treatments are highly debated. This review provides a critical appraisal of the tolerability profiles of long-acting beta2-agonists and leukotriene receptor antagonists used in combination with inhaled corticosteroids for the treatment of asthma.
- Publication
The Journal of asthma : official journal of the Association for the Care of Asthma, 2007, Vol 44, Issue 6, p411
- ISSN
0277-0903
- Publication type
Journal Article
- DOI
10.1080/02770900701247178