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- Title
Regulation of Pseudomonas aeruginosa corneal infection in IL-1 beta converting enzyme (ICE, caspase-1) deficient mice.
- Authors
Thakur, Archana; Barrett, Ronald P; McClellan, Sharon; Hazlett, Linda D
- Abstract
Antibody neutralization studies have shown that in Pseudomonas aeruginosa corneal infection, IL-1 beta is critical to regulation of the host inflammatory response, but mechanisms remain undetermined. To elucidate these mechanisms, caspase-1 knockout (ICE(-/-)) mice, that do not release mature IL-1 beta after endotoxin challenge, were tested.
- Publication
Current eye research, 2004, Vol 29, Issue 4-5, p225
- ISSN
0271-3683
- Publication type
Journal Article
- DOI
10.1080/02713680490516710