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- Title
'Recurrent' glioblastoma multiforme, when should we reoperate?
- Authors
Barbagallo, Giuseppe M V; Jenkinson, Michael D; Brodbelt, Andrew R
- Abstract
The surgical management of recurrent glioblastoma multiforme is controversial. Recent publications suggest that re-operation provides 3-5 months median survival, without significant increases in morbidity or mortality. Age (< or =50 years, although older patients may also benefit) and performance status (Karnofsky performance score > or =60-70) are the most important factors. Re-resection not only improves symptoms and maintains quality of life, it can delay symptom progression, reduce corticosteroid doses, and also improve response to (and allow intra-operative) chemotherapy and/or radiotherapy. Surgical treatment of recurrent glioblastoma multiforme in selected patients should always be considered.
- Publication
British journal of neurosurgery, 2008, Vol 22, Issue 3, p452
- ISSN
0268-8697
- Publication type
Journal Article
- DOI
10.1080/02688690802182256