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Title
Preparation of aminoglycoside-loaded chitosan nanoparticles using dextran sulphate as a counterion.
Authors
Lu, Enxian; Franzblau, Scott; Onyuksel, Hayat; Popescu, Carmen
Abstract
To prepare aminoglycoside (AG) (streptomycin, gentamicin and tobramycin) loaded chitosan nanoparticles with high drug incorporation efficiency and test the in vivo oral efficacy of streptomycin (SM) loaded chitosan nanoparticles in a Mycobacterium tuberculosis (TB) chronic infection mouse model.
Publication
Journal of microencapsulation, 2009, Vol 26, Issue 4, p346