We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Role of mesalazine in acute and long-term treatment of ulcerative colitis and its complications.
- Authors
Schroeder, K W
- Abstract
Sulfasalazine, consisting of 5-aminosalicylic acid bound to sulfapyridine by a diazo bond, was first used for treatment of ulcerative colitis in the early 1940s and later found effective in placebo-controlled trials for acute disease and for long-term maintenance of remission. Later studies found that the active moiety is 5-ASA (mesalazine, mesalamine) and the sulfapyridine moiety acts as a carrier molecule but causes many of the symptomatic adverse reactions.
- Publication
Scandinavian journal of gastroenterology. Supplement, 2002, Issue 236, p42
- ISSN
0085-5928
- Publication type
Journal Article
- DOI
10.1080/003655202320621445