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- Title
Prognostic markers of high-grade squamous intraepithelial lesions: the role of p16INK4a and high-risk human papillomavirus.
- Authors
Eleutério, José, Jr; Giraldo, Paulo César; Gonçalves, Ana Katherine; Cavalcante, Diane Isabelle Magno; de Almeida Ferreira, Francisco Valdeci; Mesquita, Suzana Moreira; Morais, Sirlei Siani
- Abstract
p16INK4a seems to be an indicator of the grade of Human Papillomavirus-induced lesions and a possible predictor of the lesion evolution. There are few studies about the role of HPV test and p16INK4a in diagnosis of high-grade cervical lesions in South-American women. The aim of the present study was to evaluate the presence of p16INK4a and high-risk HPV-DNA expression in cases diagnosed as squamous intra-epithelial lesion and evaluate their role in the approach of high-grade squamous intra-epithelial lesion.
- Publication
Acta obstetricia et gynecologica Scandinavica, 2007, Vol 86, Issue 1, p94
- ISSN
0001-6349
- Publication type
Journal Article
- DOI
10.1080/00016340601089727