Title

Catalase in the Stratum Corneum of Patients with Polymorphic Light Eruption.

Authors

Guarrera, M.; Ferrari, P.; Rebora, A.

Abstract

UV radiation generates reactive oxygen species, which may be involved in polymorphic light eruption. The endogenous enzymatic defense system includes catalase in the epidermis. Thirteen patients with a history of polymorphic light eruption, but free from lesions, and 13 controls were investigated from November to March. Catalase was analysed in the upper horny layer according to Colin et al.'s spectrophotometric technique. In polymorphic light eruption, catalase values were about 30% lower than in control subjects. Such deficiency was observed in patients free from the disease and not recently sun-exposed. The diminished skin catalase in irradiated polymorphic light eruption makes it possible that a longer restoration time of catalase is involved in the pathogenesis.

Subjects

CATALASE; EPIDERMAL diseases; OXYGEN in the body; PHYSIOLOGY

Publication

Acta Dermato-Venereologica, 1998, Vol 78, Issue 5, p335

ISSN

0001-5555

Publication type

Academic Journal

DOI

10.1080/000155598442999