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- Title
Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding.
- Authors
Chan, Francis K L; Ching, Jessica Y L; Hung, Lawrence C T; Wong, Vincent W S; Leung, Vincent K S; Kung, Nelson N S; Hui, Aric J; Wu, Justin C Y; Leung, Wai K; Lee, Vivian W Y; Lee, Kenneth K C; Lee, Yuk T; Lau, James Y W; To, Ka F; Chan, Henry L Y; Chung, S C Sydney; Sung, Joseph J Y
- Abstract
Concurrent therapy with a proton-pump inhibitor is a standard treatment for patients receiving aspirin who are at risk for ulcer. Current U.S. guidelines also recommend clopidrogel for patients who have major gastrointestinal intolerance of aspirin. We compared clopidogrel with aspirin plus esomeprazole for the prevention of recurrent bleeding from ulcers in high-risk patients.
- Publication
The New England journal of medicine, 2005, Vol 352, Issue 3, p238
- ISSN
1533-4406
- Publication type
Journal Article
- DOI
10.1056/NEJMoa042087