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- Title
The interleukin-6 -174 G/C promoter polymorphism is associated with risk of coronary heart disease and systolic blood pressure in healthy men.
- Authors
Humphries, S E; Luong, L A; Ogg, M S; Hawe, E; Miller, G J
- Abstract
Inflammation is a key component of coronary heart disease, and genes coding for cytokines are candidates for predisposing to coronary heart disease risk. We have examined the effect of two polymorphisms (-174G>C and -572G>C) in the promoter of the interleukin-6 (IL-6) gene on risk of coronary heart disease, and on intermediate risk traits including fibrinogen and systolic blood pressure, in 2751 middle-aged healthy U.K. men.
- Publication
European heart journal, 2001, Vol 22, Issue 24, p2243
- ISSN
0195-668X
- Publication type
Journal Article
- DOI
10.1053/euhj.2001.2678