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- Title
NADH/NADPH oxidase p22 phox gene polymorphism is associated with improved coronary endothelial vasodilator function.
- Authors
Schächinger, V; Britten, M B; Dimmeler, S; Zeiher, A M
- Abstract
The NADH/NADPH oxidase system plays a central role in vascular superoxide anion production, which appears to cause coronary endothelial dysfunction. Recently, it has been suggested that the C242T polymorphism of the NADH/NADPH oxidase p22 phox gene can reduce susceptibility to coronary artery disease. We therefore tested whether this polymorphism is associated with an altered endothelium-dependent vasodilator capacity of human coronary arteries in vivo.
- Publication
European heart journal, 2001, Vol 22, Issue 1, p96
- ISSN
0195-668X
- Publication type
Journal Article
- DOI
10.1053/euhj.2000.2123