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Title
MP4, a new nonvasoactive PEG-Hb conjugate.
Authors
Vandegriff, Kim D; Malavalli, Ashok; Wooldridge, Jerod; Lohman, Jeff; Winslow, Robert M
Abstract
Vasoconstriction has been an obstacle to clinical development of Hb-based O2 carriers. It is proposed that this limitation can be overcome by increasing molecular size and oxygen affinity.