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- Title
C5a delays apoptosis of human neutrophils by a phosphatidylinositol 3-kinase-signaling pathway.
- Authors
Perianayagam, Mary C; Balakrishnan, V S; King, Andrew J; Pereira, Brian J G; Jaber, Bertrand L
- Abstract
Studies have shown that survival factors including cytokines and growth factors delay apoptosis of human neutrophils via induction of the phosphatidylinositol-3 kinase (PI 3-K)/Akt pathway. In the present study, we explored whether complement fragment C5a has a modulatory effect on neutrophil apoptosis through this signaling pathway.
- Publication
Kidney international, 2002, Vol 61, Issue 2, p456
- ISSN
0085-2538
- Publication type
Journal Article
- DOI
10.1046/j.1523-1755.2002.00139.x