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Title
PAI-1 deficiency attenuates the fibrogenic response to ureteral obstruction.
Authors
Oda, T; Jung, Y O; Kim, H S; Cai, X; López-Guisa, J M; Ikeda, Y; Eddy, A A
Abstract
Progressive renal disease is characterized by the induction of plasminogen activator inhibitor-1 (PAI-1), suggesting that impaired activity of the renal plasmin cascade may play a role in renal fibrosis.