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Title
Impact of interleukin-1 receptor antagonist and tumor necrosis factor-α gene polymorphism on IgA nephropathy.
Authors
Kuo-Hsiung Shu; Shen-Huey Lee; Chi-Hung Cheng; Ming-Ju Wu; Jong-Da Lian
Abstract
Focuses on the impact of interleukin-1 receptor on the tumor necrosis factor-alpha gene polymorhism on nephropathy. Role of cytokines in the pathogenesis; Involvement of guanidine to adenosine transition in polymorphism; Relevance of IL-1ra or IL-1 blocking agent treatment of IL1RN*2 allele.