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- Title
Predominant nocturnal acid reflux in patients with Los Angeles grade C and D reflux esophagitis.
- Authors
Adachi, K; Fujishiro, H; Katsube, T; Yuki, M; Ono, M; Kawamura, A; Rumi, M A; Watanabe, M; Kinoshita, Y
- Abstract
Nocturnal gastric acid breakthrough (NAB) is defined as an intragastric pH < 4.0 lasting more than 1 h during the night in patients taking a proton pump inhibitor (PPI). Gastroesophageal reflux disease (GERD) patients with nocturnal gastroesophageal acid reflux accompanied by NAB are thought to be refractory to PPI treatment. The aim of this study was to endoscopically identify the patients with predominant nocturnal gastroesophageal acid reflux.
- Publication
Journal of gastroenterology and hepatology, 2001, Vol 16, Issue 11, p1191
- ISSN
0815-9319
- Publication type
Journal Article
- DOI
10.1046/j.1440-1746.2001.02617.x