We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Polypeptide neurotoxins from spider venoms.
- Authors
Grishin, E
- Abstract
Spider venoms contain a variety of toxic components. The polypeptide toxins are divided into low and high molecular mass types. Small polypeptide toxins interacting with cation channels display spatial structure homology. They can affect the functioning of calcium, sodium, or potassium channels. A family of high molecular mass toxic proteins was found in the venom of the spider genus Latrodectus. These neurotoxins, latrotoxins, cause a massive transmitter release from a diversity of nerve endings. The latrotoxins are proteins of about 1000 amino acid residues and share a high level of structure identity. The structural and functional properties of spider polypeptide toxins are reviewed in this paper.
- Publication
European journal of biochemistry, 1999, Vol 264, Issue 2, p276
- ISSN
0014-2956
- Publication type
Journal Article
- DOI
10.1046/j.1432-1327.1999.00622.x