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- Title
Normohomocysteinaemia and vitamin-treated hyperhomocysteinaemia are associated with similar risks of cardiovascular events in patients with premature peripheral arterial occlusive disease. A prospective cohort study.
- Authors
de Jong, S C; Stehouwer, C D; van den Berg, M; Geurts, T W; Bouter, L M; Rauwerda, J A
- Abstract
Mild hyperhomocysteinaemia (HHC), fasting or after methionine loading, is associated with an increased risk and severity of atherosclerotic vascular disease. Post-methionine and fasting HHC are responsive to treatment with vitamin B, and folic acid. We performed a prospective cohort study amongst normohomocysteinaemic and vitamin-treated (vitamin B6, 250 mg plus folic acid, 5 mg daily) hyperhomocysteinaemic patients with premature peripheral arterial occlusive disease and assessed the incidence of cardiovascular events.
- Publication
Journal of internal medicine, 1999, Vol 246, Issue 1, p87
- ISSN
0954-6820
- Publication type
Journal Article
- DOI
10.1046/j.1365-2796.1999.00541.x