We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Improvement of symptoms in infant colic following reduction of lactose load with lactase.
- Authors
Kanabar, D; Randhawa, M; Clayton, P
- Abstract
Transient lactose intolerance has been identified as a possible causative factor in infant colic. A double-blind randomised placebo-controlled crossover study to investigate this has been undertaken in 53 babies with symptoms of colic. Pre-incubation of the feed with lactase resulted in breath hydrogen levels and total crying time which were both at least 45% lower than figures with placebo treatment, in 26% of the full trial group (95% confidence interval 12.9% to 44.4%), and in 38% of compliers (95% confidence interval 18.8% to 59.4%). The remainder did not respond to the same extent. These findings suggest that infant colic may have a multiple aetiology, and that in a significant number of cases the immediate cause is transient lactose intolerance, in which cases pretreatment of feeds with lactase can result in considerable symptomatic benefits.
- Publication
Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 2001, Vol 14, Issue 5, p359
- ISSN
0952-3871
- Publication type
Journal Article
- DOI
10.1046/j.1365-277x.2001.00304.x