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- Title
Evaluation of DNA topoisomerase IIalpha expression provides independent prognostic information in non-Hodgkin's lymphomas.
- Authors
Korkolopoulou, P; Angelopoulou, M; Siakantari, M; Mitropoulos, F; Vassilakopoulos, T; Zorzos, H; Rassidakis, G; Androulaki, A; Patsouris, E; Kittas, C; Davaris, P; Pangalis, G A
- Abstract
In view of the dual role that DNA topoisomerase IIa (TopoIIa) plays as a cell proliferation marker and as a possible indicator of chemosensitivity, we investigated its expression in non-Hodgkin's lymphomas (NHL) in relation to conventional clinicopathological parameters, cell proliferation (as defined by Ki67 immunoreactivity), response to therapy and patient outcome.
- Publication
Histopathology, 2001, Vol 38, Issue 1, p45
- ISSN
0309-0167
- Publication type
Journal Article
- DOI
10.1046/j.1365-2559.2001.01036.x