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- Title
Identification and characterization of DAlk: a novel Drosophila melanogaster RTK which drives ERK activation in vivo.
- Authors
Lorén, C E; Scully, A; Grabbe, C; Edeen, P T; Thomas, J; McKeown, M; Hunter, T; Palmer, R H
- Abstract
The mammalian receptor protein tyrosine kinase (RTK), Anaplastic Lymphoma Kinase (ALK), was first described as the product of the t(2;5) chromosomal translocation found in non-Hodgkin's lymphoma. While the mechanism of ALK activation in non-Hodgkin's lymphoma has been examined, to date, no in vivo role for this orphan insulin receptor family RTK has been described.
- Publication
Genes to cells : devoted to molecular & cellular mechanisms, 2001, Vol 6, Issue 6, p531
- ISSN
1356-9597
- Publication type
Journal Article
- DOI
10.1046/j.1365-2443.2001.00440.x