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- Title
Human ubiquitin-protein ligase Nedd4: expression, subcellular localization and selective interaction with ubiquitin-conjugating enzymes.
- Authors
Anan, T; Nagata, Y; Koga, H; Honda, Y; Yabuki, N; Miyamoto, C; Kuwano, A; Matsuda, I; Endo, F; Saya, H; Nakao, M
- Abstract
Nedd4 is a ubiquitin-protein ligase containing a calcium/lipid-binding domain, multiple WW domains and a C-terminal Hect domain, which is required for both the ubiquitin transfer and the association with E2 ubiquitin-conjugating enzymes. Nedd4 has been reported to be involved in the selective ubiquitination of some regulatory proteins in transcription and membrane transport.
- Publication
Genes to cells : devoted to molecular & cellular mechanisms, 1998, Vol 3, Issue 11, p751
- ISSN
1356-9597
- Publication type
Journal Article
- DOI
10.1046/j.1365-2443.1998.00227.x