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- Title
Enhancement of allergic skin wheal responses in patients with atopic eczema/dermatitis syndrome by playing video games or by a frequently ringing mobile phone.
- Authors
Kimata, H
- Abstract
Playing video games causes physical and psychological stress, including increased heart rate and blood pressure and aggression-related feelings. Use of mobile phones is very popular in Japan, and frequent ringing is a common and intrusive part of Japanese life. Atopic eczema/dermatitis syndrome is often exacerbated by stress. Stress increases serum IgE levels, skews cytokine pattern towards Th2 type, enhances allergen-induced skin wheal responses, and triggers mast cell degranulation via substance P, vasoactive intestinal peptide and nerve growth factor.
- Publication
European journal of clinical investigation, 2003, Vol 33, Issue 6, p513
- ISSN
0014-2972
- Publication type
Journal Article
- DOI
10.1046/j.1365-2362.2003.01177.x