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- Title
The atherogenic plasma remnant-like particle cholesterol concentration is increased in the fasting and postprandial state in active acromegalic patients.
- Authors
Twickler, T B; Dallinga-Thie, G M; Zelissen, P M; Koppeschaar, H P; Erkelens, D W
- Abstract
Premature atherosclerosis is a clinical feature in untreated acromegaly. Increased postprandial lipoprotein remnant levels are associated with premature atherosclerosis. In most studies, remnants have been measured indirectly using retinyl esters (RE) as a chylomicron core label. Remnants can also be directly quantified by immunoseparation using monoclonal antibodies to apolipoprotein (apo) AI and apo B100 to remove nonremnant lipoproteins. Cholesterol is quantified in the remaining apo E-rich remnant fraction (RLP-C).
- Publication
Clinical endocrinology, 2001, Vol 55, Issue 1, p69
- ISSN
0300-0664
- Publication type
Journal Article
- DOI
10.1046/j.1365-2265.2001.01326.x