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- Title
Sleep deprivation effects on the activity of the hypothalamic-pituitary-adrenal and growth axes: potential clinical implications.
- Authors
Vgontzas, A N; Mastorakos, G; Bixler, E O; Kales, A; Gold, P W; Chrousos, G P
- Abstract
Although several studies have shown that sleep deprivation is associated with increased slow wave sleep during the recovery night, the effects of sleep deprivation on cortisol and growth hormone (GH) secretion the next day and recovery night have not been assessed systematically. We hypothesized that increased slow wave sleep postsleep deprivation is associated with decreased cortisol levels and that the enhanced GH secretion is driven by the decreased activity of the HPA axis.
- Publication
Clinical endocrinology, 1999, Vol 51, Issue 2, p205
- ISSN
0300-0664
- Publication type
Journal Article
- DOI
10.1046/j.1365-2265.1999.00763.x