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- Title
Inhibin B levels in azoospermic subjects with cytologically characterized testicular pathology.
- Authors
Foresta, C; Bettella, A; Petraglia, F; Pistorello, M; Luisi, S; Rossato, M
- Abstract
Inhibin B, a heterodimeric glycoprotein of gonadal origin, is the most important circulating form of inhibin in human males and an inverse relationship between inhibin B and FSH plasma levels was been recently observed. Azoospermia represents the end-point of different kinds of testicular damage, ranging from a normal spermatogenic pattern (obstructive forms) to the complete absence of germ cells (Sertoli Cell Only Syndrome, SCOS). Furthermore, azoospermia may be related to maturational disturbances at different levels (spermatogonial, spermatocytic, spermatidic). To better define the relationship between testicular damage and inhibin levels and to evaluate the diagnostic value of this hormone in the management of subjects with azoospermia, we performed specific inhibin B assays in a group of azoospermic subjects affected by different kinds of testicular pathology.
- Publication
Clinical endocrinology, 1999, Vol 50, Issue 6, p695
- ISSN
0300-0664
- Publication type
Journal Article
- DOI
10.1046/j.1365-2265.1999.00659.x