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- Title
The effect of six months treatment with a 100 mg daily dose of dehydroepiandrosterone (DHEA) on circulating sex steroids, body composition and muscle strength in age-advanced men and women.
- Authors
Morales, A J; Haubrich, R H; Hwang, J Y; Asakura, H; Yen, S S
- Abstract
The biological role of the adrenal sex steroid precursors--DHEA and DHEA sulphate (DS) and their decline with ageing remains undefined. We observed previously that administration of a 50 daily dose of DHEA for 3 months to age-advanced men and women resulted in an elevation (10%) of serum levels of insulin-like growth factor-I (IGF-I) accompanied by improvement of self-reported physical and psychological well-being. These findings led us to assess the effect of a larger dose (100 mg) of DHEA for a longer duration (6 months) on circulating sex steroids, body composition (DEXA) and muscle strength (MedX).
- Publication
Clinical endocrinology, 1998, Vol 49, Issue 4, p421
- ISSN
0300-0664
- Publication type
Journal Article
- DOI
10.1046/j.1365-2265.1998.00507.x