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- Title
Comparison of cytokine secretion profiles provoked in mice by glutaraldehyde and formaldehyde.
- Authors
Dearman, R J; Basketter, D A; Evans, P; Kimber, I
- Abstract
Glutaraldehyde and formaldehyde are commonly used sterilizing agents that are known skin sensitizers. There is some controversy, however, regarding their capacity to cause respiratory allergy. The authors have demonstrated previously that topical exposure of mice to chemical contact allergens such as 2,4-dinitrochlorobenzene (DNCB) or respiratory allergens such as trimellitic anhydride (TMA) induces characteristic cytokine secretion profiles consistent with the selective activation of T helper1 (TH1)- and TH2-type cells, respectively.
- Publication
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1999, Vol 29, Issue 1, p124
- ISSN
0954-7894
- Publication type
Journal Article
- DOI
10.1046/j.1365-2222.1999.00437.x