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- Title
Pseudotumour of the tongue caused by herpes simplex virus type 2 in an HIV-1 infected immunosuppressed patient.
- Authors
Husak, R; Tebbe, B; Goerdt, S; Wölfer, L U; Zeichardt, H; Stöffler-Meilicke, M; Orfanos, C E
- Abstract
An HIV-1 infected immunosuppressed patient (CD4+ cell counts: 382 cells/microL; viral load 94,000 copies/mL) with recurrent perianal herpes simplex virus type 2 (HSV-2) infections is described, showing an unusual exophytic tumour resembling a squamous cell carcinoma in the lateral part of the tongue. He also had persistent facial herpes infection, oral candidosis, oral hairy leukoplakia and lymphadenopathy. The presence of HSV-2 was detected by polymerase chain reaction both in smears and in a tissue biopsy taken from the involved tongue area. Treatment with brivudin, a new oral virustatic drug, led to rapid regression of the tumour.
- Publication
The British journal of dermatology, 1998, Vol 139, Issue 1, p118
- ISSN
0007-0963
- Publication type
Journal Article
- DOI
10.1046/j.1365-2133.1998.02327.x