We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Effect of Helicobacter pylori eradication on expression of cyclin D2 and p27 in gastric intestinal metaplasia.
- Authors
Yu, J; Leung, W K; Ng, E K; To, K F; Ebert, M P; Go, M Y; Chan, W Y; Chan, F K; Chung, S C; Malfertheiner, P; Sung, J J
- Abstract
Cyclins and cyclin-dependent kinase inhibitors play a crucial role in the control of cell cycle transitions. Enhanced expression of cyclin D2 and reduced expression of p27kip1 (p27) have been implicated in the pathogenesis of cancer. Because intestinal metaplasia has been regarded as a pre-malignant lesion, we investigated the expression of cyclin D2 and p27 in Helicobacter pylori-associated chronic gastritis with and without intestinal metaplasia, and followed the changes after H. pylori eradication.
- Publication
Alimentary pharmacology & therapeutics, 2001, Vol 15, Issue 9, p1505
- ISSN
0269-2813
- Publication type
Journal Article
- DOI
10.1046/j.1365-2036.2001.01038.x