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- Title
Limitation of the in vitro whole blood assay for predicting the COX selectivity of NSAIDs in clinical use.
- Authors
Blain, Hubert; Boileau, Christelle; Lapicque, Françoise; Nédélec, Emmanuelle; Loeuille, Damien; Guillaume, Cécile; Gaucher, Alain; Jeandel, Claude; Netter, Patrick; Jouzeau, Jean-Yves
- Abstract
To assess if the inhibitory potency of nonsteroidal anti-inflammatory drugs (NSAIDs) on cyclooxygenase (COX) isoenzymes, when given therapeutically in humans, can be predicted from their in vitro concentration-response curves using the whole blood assay.
- Publication
British journal of clinical pharmacology, 2002, Vol 53, Issue 3, p255
- ISSN
0306-5251
- Publication type
Journal Article
- DOI
10.1046/j.0306-5251.2001.01533.x