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- Title
Molecular diagnostics of gliomas.
- Authors
Nikiforova, Marina N; Hamilton, Ronald L
- Abstract
Gliomas are the most common primary brain tumors of adults and include a variety of histologic types and morphologies. Histologic evaluation remains the gold standard for glioma diagnosis; however, diagnostic difficulty may arise from tumor heterogeneity, overlapping morphologic features, and tumor sampling. Recently, our knowledge about the genetics of these tumors has expanded, and new molecular markers have been developed. Some of these markers have shown diagnostic value, whereas others are useful prognosticators for patient survival and therapeutic response.
- Publication
Archives of pathology & laboratory medicine, 2011, Vol 135, Issue 5, p558
- ISSN
1543-2165
- Publication type
Journal Article
- DOI
10.1043/2010-0649-RAIR.1