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- Title
Mechanisms of microbial escape from phagocyte killing.
- Authors
Smith, Leanne M; May, Robin C
- Abstract
Phagocytosis and phagosome maturation are crucial processes in biology. Phagocytosis and the subsequent digestion of phagocytosed particles occur across a huge diversity of eukaryotes and can be achieved by many different cells within one organism. In parallel, diverse groups of pathogens have evolved mechanisms to avoid killing by phagocytic cells. The present review discusses a key innate immune cell, the macrophage, and highlights the myriad mechanisms microbes have established to escape phagocytic killing.
- Publication
Biochemical Society transactions, 2013, Vol 41, Issue 2, p475
- ISSN
1470-8752
- Publication type
Journal Article
- DOI
10.1042/BST20130014