Works matching DE "TOR proteins"

Results: 342

Genetic correlates of malignancy in TFE3‐rearranged PEComa: a series of 14 cases.

Published in:

Histopathology, 2025, v. 87, n. 3, p. 436, doi. 10.1111/his.15476

By:

Papke, David J;
Odintsov, Igor;
Mahadevan, Navin R;
Fletcher, Christopher DM;
Hanna, John

Publication type:

Article

Dual PI3K/mTOR inhibitor NVP-BEZ235 induces cell cycle arrest via autophagy mediated protein degradation of RPL19 in nephroblastoma cell.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1588722

By:

Gao, Yan;
Xing, Xinran;
Cai, Ruizhi;
Liu, Dong;
Feng, Qili;
Luo, Jiaqi;
Zhu, Yongzhao;
Su, Zeli

Publication type:

Article

Exploring the mechanism of pachymic acid intervention in myocardial ischemia based on network pharmacology and experimental validation.

Published in:

Journal of Pharmacy & Pharmacology, 2025, v. 77, n. 7, p. 944, doi. 10.1093/jpp/rgae153

By:

Yin, Nengpin;
Zhao, Xuan;
Yang, Jin;
Liu, Zongjun

Publication type:

Article

Polyphenol-rich extract from Wisteria floribunda (Willd.) DC. flowers promotes osteoblast differentiation and bone formation by modulating the mTOR pathway.

Published in:

Asian Pacific Journal of Tropical Biomedicine, 2025, v. 15, n. 8, p. 313, doi. 10.4103/apjtb.apjtb_89_25

By:

Jayasingha, Jayasingha Arachchige Chathuranga Chanaka;
Lee, Kyoung Tae;
Jin, Cheng-Yun;
Choi, Yung Hyun;
Lee, Chang Soo;
Jung, Min-Jeong;
Kim, Gi-Young

Publication type:

Article

Oncogenic CMTM6 drives M2a macrophages formation and fuels cervical cancer progression.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1621816

By:

Yin, Bo;
Chen, Chun;
Huang, Baoyou;
Ding, Jianyi;
Hu, Haoran;
Zhou, Huijuan;
Zhu, Yashi;
Huang, Tiefeng;
He, Xiang;
Lu, Yuan;
Han, Lingfei

Publication type:

Article

Long non-coding RNA NORAD serves as a promoter of oncogenesis and inhibits ferroptosis via miR-144-3p-mTOR-ferritinophagy axis in cancer.

Published in:

European Journal of Medical Research, 2025, v. 30, n. 1, p. 1, doi. 10.1186/s40001-025-02998-2

By:

Zhang, Xuefei;
Zheng, Wei;
Li, Haixia;
Zhang, Lei;
Zhao, Haidong;
Sui, Shiyao;
Cheng, Wen

Publication type:

Article

Muscle‐specific AXIN1 and AXIN2 double knockout does not alter AMPK/mTORC1 signalling or glucose metabolism.

Published in:

Journal of Physiology, 2025, v. 603, n. 14, p. 3961, doi. 10.1113/JP288854

By:

Persson, Kaspar W.;
Meneses‐Valdés, Roberto;
Andersen, Nicoline R.;
Pedersen, Frederik S.;
Gallero, Samantha;
Hesselager, Sofie A.;
Henriquez‐Olguin, Carlos;
Jensen, Thomas E.

Publication type:

Article

P16-positive senescent cells promote DKD by the dysregulation of glycolysis and mitochondrial metabolism.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02650-2

By:

Lu, Xiao;
Wu, Jiao;
Agborbesong, Ewud;
Li, Xiaogang

Publication type:

Article

Integrated transcriptomic and functional modeling reveals AKT and mTOR synergy in colorectal cancer.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-08649-0

By:

Duleba, Marcin;
Zimoląg, Eliza;
Szuszkiewicz, Joanna;
Serocki, Marcin;
Szklarczyk, Joanna;
Dracz, Olga;
Kurzejamski, Alexander;
Więckowska, Izabella;
Chmiel, Marcelina;
Lipert, Barbara;
Sarad, Katarzyna;
Krawczyk, Joanna;
Bryzghalov, Oleksii;
Stachowicz-Wałaszek, Agata;
Pyziak, Karolina;
Drozdowska, Joanna;
Baczyński, Krzysztof;
Wojtowicz, Konrad;
Chronowski, Maurycy;
Rataj, Krzysztof

Publication type:

Article

Light-dark dependent changes in chloroplast and mitochondrial activity in Chlamydomonas reinhardtii.

Published in:

Frontiers in Plant Science, 2025, p. 1, doi. 10.3389/fpls.2025.1622214

By:

Dhawan, Gunjan;
Rao, Basuthkar Jagadeeshwar

Publication type:

Article

Does taking L-Carnitine and Cadmium have an impact on gene expression of the liver tissues from rat models?

Published in:

Bangladesh Journal of Medical Science, 2025, v. 24, n. 2, p. 614, doi. 10.3329/bjms.v24i2.81728

By:

ABDULMOHSIN, Duaa;
AYTACOGLU, Hakan;
KOCAMAZ, Gamze;
KUKNER, Aysel;
TULAY, Pınar

Publication type:

Article

TIPRL, a Potential Double-edge Molecule to be Targeted and Re-targeted Toward Cancer.

Published in:

Cell Biochemistry & Biophysics, 2024, v. 82, n. 3, p. 1681, doi. 10.1007/s12013-024-01334-5

By:

Gao, Jie;
You, Tiantian;
Liu, Jiao;
Yang, Lili;
Liu, Yan;
Wang, Yanyan

Publication type:

Article

Flavonoids for Myocardial Ischemia–Reperfusion Injury?

Published in:

Cardiovascular Drugs & Therapy, 2025, v. 39, n. 4, p. 705, doi. 10.1007/s10557-025-07688-z

By:

Birnbaum, Yochai;
Vilahur, Gemma

Publication type:

Article

From pathogenesis of acne vulgaris to anti-acne agents.

Published in:

Archives of Dermatological Research, 2019, v. 311, n. 5, p. 337, doi. 10.1007/s00403-019-01908-x

By:

Cong, Tian-Xin;
Hao, Dan;
Wen, Xiang;
Li, Xiao-Hua;
He, Gu;
Jiang, Xian

Publication type:

Article

ROS Generated by Upconversion Nanoparticle-Mediated Photodynamic Therapy Induces Autophagy Via PI3K/AKT/ mTOR Signaling Pathway in M1 Peritoneal Macrophage.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2018, v. 48, n. 4, p. 1616, doi. 10.1159/000492283

By:

Han, Xiaobo;
Zhong, Zhaoyu;
Zheng, Yinghong;
Liu, Zhongni;
Jiang, Yueqing;
Gao, Ziyu;
Cong, Lin;
Yang, Liming;
Tian, Ye;
Kou, Jiayuan;
Zhang, Zhiren

Publication type:

Article

Blocking Mammalian Target of Rapamycin (mTOR) Alleviates Neuropathic Pain Induced by Chemotherapeutic Bortezomib.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2018, v. 48, n. 1, p. 54, doi. 10.1159/000491662

By:

Duan, Zongsheng;
Li, Jing;
Pang, Xiaochuan;
Wang, Hushan;
Su, Zhenbo

Publication type:

Article

Partially non-homogeneous dynamic Bayesian networks based on Bayesian regression models with partitioned design matrices.

Published in:

Bioinformatics, 2019, v. 35, n. 12, p. 2108, doi. 10.1093/bioinformatics/bty917

By:

Kamalabad, Mahdi Shafiee;
Heberle, Alexander Martin;
Thedieck, Kathrin;
Grzegorczyk, Marco

Publication type:

Article

"TRIMing" the Patient Population to Increase the Benefit of mTOR Inhibition.

Published in:

2014

By:

Robins, H. Ian;
Burkard, Mark E.;
Halberg, Richard B.

Publication type:

Editorial

Valproate independently activates Snf1, inhibits TORC1, and induces repression of INO1 transcription by increasing nuclear localization of Opi1.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-07540-2

By:

Case, Kendall C.;
Orkun, Lara;
Greenberg, Miriam L.

Publication type:

Article

PTEN deficiency in postnatally developing Purkinje cells disrupts metabolic signaling, leading to dendritic abnormalities and sex-specific behavioral deficits.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-09059-y

By:

Walsh, Lindsay J.;
Espinal-San Miguel, Izabella M.;
Rodriguez, Ana V.;
Peña, Ursula M.;
Flynn, Kiley E.;
Remillard, Will C.;
Brazier, Siena R.;
Anderson, Natalia I.;
Clark, Aidan J.;
De Varona, Tiffany A.;
Soto, Ileana

Publication type:

Article

Activation of the TOR Signalling Pathway by Glutamine Regulates Insect Fecundity.

Published in:

Scientific Reports, 2015, p. 10694, doi. 10.1038/srep10694

By:

Zhai, Yifan;
Sun, Zhongxiang;
Zhang, Jianqing;
Kang, Kui;
Chen, Jie;
Zhang, Wenqing

Publication type:

Article

Target of Rapamycin Complex 2 regulates cell growth via Myc in Drosophila.

Published in:

Scientific Reports, 2015, p. 10339, doi. 10.1038/srep10339

By:

Kuo, Ying;
Huang, Huanwei;
Cai, Tao;
Wang, Tao

Publication type:

Article

FTO – A Common Genetic Basis for Obesity and Cancer.

Published in:

Frontiers in Genetics, 2020, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.559138

By:

Lan, Ning;
Lu, Ying;
Zhang, Yigan;
Pu, Shuangshuang;
Xi, Huaze;
Nie, Xin;
Liu, Jing;
Yuan, Wenzhen

Publication type:

Article

Absence of m TOR Inhibitor Effect on Hepatic Cyst Growth: A Case Report of a Kidney Transplant Recipient with Autosomal Dominant Polycystic Kidney Disease.

Published in:

Case Reports in Transplantation, 2012, p. 1, doi. 10.1155/2012/513025

By:

Friedrich, L.;
Barbey, F.;
Pascual, M.;
Venetz, J.-P.

Publication type:

Article

Association of Rictor with chromosomes during mitosis in MCF7 cells.

Published in:

Biopolymers & Cell, 2015, v. 31, n. 6, p. 422, doi. 10.7124/bc.0008FF

By:

Malanchuk, O. M.

Publication type:

Article

Development of monoclonal antibody against protein Rictor, a component of the mTORC2 complex.

Published in:

Biopolymers & Cell, 2015, v. 31, n. 5, p. 379, doi. 10.7124/bc.0008FA

By:

Malanchuk, O. M.

Publication type:

Article

Evolution of growth factor signaling to the TSC complex to regulate mTORC1.

Published in:

Science Signaling, 2025, v. 18, n. 894, p. 1, doi. 10.1126/scisignal.adw4165

By:

Wang, Kun;
Lockwood, Sophie E.;
Manning, Brendan D.

Publication type:

Article

Regulation of the Ras-MAPK and PI3K-mTOR Signalling Pathways by Alternative Splicing in Cancer.

Published in:

International Journal of Cell Biology, 2013, p. 1, doi. 10.1155/2013/568931

By:

Siegfried, Zahava;
Bonomi, Serena;
Ghigna, Claudia;
Karni, Rotem

Publication type:

Article

The Effects of Evening Primrose/Hemp Seed Oil Compared to Rapamycin on the Gene Expression of Immunological Parameters in Experimental Autoimmune Encephalomyelitis Splenocytes.

Published in:

Iranian Journal of Allergy, Asthma & Immunology, 2020, v. 19, n. 2, p. 183

By:

Soheila Rezapour-Firouzi;
Mahshid Mohammadian;
Maryam Sadeghzadeh;
Sahar Mehranfar;
Ebrahim Mazloomi

Publication type:

Article

Transcriptomic Landscape of Polypide Development in the Freshwater Bryozoan Cristatella mucedo: From Budding to Degeneration.

Published in:

Journal of Experimental Zoology Part B: Molecular & Developmental Evolution, 2025, v. 344, n. 3, p. 119, doi. 10.1002/jez.b.23285

By:

Kvach, A. Yu.;
Kutyumov, V. A.;
Starunov, V. V.;
Ostrovsky, A. N.

Publication type:

Article

Huangqi Decoction Serum Suppressed Proliferation and Migration of Rat Liver Sinusoidal Endothelial Cells via Angiogenesis Inhibition by Promoting AKT/mTOR-Dependent Autophagy.

Published in:

Indian Journal of Pharmaceutical Sciences, 2024, v. 86, n. 3, p. 1058, doi. 10.36468/pharmaceutical-sciences.1364

By:

CHENGYI WAN;
TIANLU HOU;
YANG CHENG

Publication type:

Article

Mechanism of Puerarin Regulating AMPK/mTOR Activated Autophagy Signal Pathway in the Treatment of Diabetic Nephropathy.

Published in:

Indian Journal of Pharmaceutical Sciences, 2023, v. 85, n. 5, p. 1512

By:

HONGXIA SU;
YUAN JANG;
JIHONG LV;
XUEYING GONG;
JIE WANG;
WENJUAN YANG

Publication type:

Article

In Silico and In Vitro Perspective to Elucidate the Anticancer Effect of Natural Compound Hesperetin in Inhibiting Mammalian Target of Rapamycin Pathway.

Published in:

Indian Journal of Pharmaceutical Sciences, 2021, v. 83, n. 5, p. 989, doi. 10.36468/pharmaceutical-sciences.852

By:

JAGANATHAN, S. S.;
ROBINSON, GLORIA JEMMI CHRISTOBEL;
PADMANABAN, ABIRAMI;
SAMUEL, SHILA;
RADHAKRISHNAN, V.

Publication type:

Article

Effects of Astragaloside on Biological Characteristics of Non-Small Cell Lung Cancer Cells via the Phosphatidylinositol 3-Kinase/Protein Kinase B/Mechanistic Target of Rapamycin Pathway.

Published in:

Indian Journal of Pharmaceutical Sciences, 2021, v. 83, n. 4, p. 865, doi. 10.36468/pharmaceutical-sciences.838

By:

YUXIA LIU;
YUE ZHAO;
PENG, Z.;
LI, S.;
AISHUAI WANG;
ZHENG, X.

Publication type:

Article

Time now to TORC the TORC? New developments in m TOR pathway inhibition in lymphoid malignancies.

Published in:

British Journal of Haematology, 2014, v. 166, n. 3, p. 336, doi. 10.1111/bjh.12945

By:

Eyre, Toby A.;
Collins, Graham P.;
Goldstone, Anthony H.;
Cwynarski, Kate

Publication type:

Article

Outcomes in patients with relapsed or refractory multiple myeloma in a phase I study of everolimus in combination with lenalidomide.

Published in:

British Journal of Haematology, 2014, v. 166, n. 3, p. 401, doi. 10.1111/bjh.12909

By:

Yee, Andrew J.;
Hari, Parameswaran;
Marcheselli, Raffaella;
Mahindra, Anuj K.;
Cirstea, Diana D.;
Scullen, Tyler A.;
Burke, Jill N.;
Rodig, Scott J.;
Hideshima, Teru;
Laubach, Jacob P.;
Ghobrial, Irene M.;
Schlossman, Robert L.;
Munshi, Nikhil C.;
Anderson, Kenneth C.;
Weller, Edie A.;
Richardson, Paul G.;
Raje, Noopur S.

Publication type:

Article

Orchestrating Neural Development Through mRNA Translation Regulation.

Published in:

Journal of Neurochemistry, 2025, v. 169, n. 6, p. 1, doi. 10.1111/jnc.70128

By:

Rodrigue, Brandon;
Sajish, Mathew;
Salmaso, Natalina;
Aguilar‐Valles, Argel

Publication type:

Article

Hippocampal Inhibitory Interneuron‐Specific DREADDs Treatment Alters mTORC1‐4E‐BP Signaling and Impairs Memory Formation.

Published in:

Journal of Neurochemistry, 2025, v. 169, n. 3, p. 1, doi. 10.1111/jnc.70048

By:

Huang, Ziying;
Mahmood, Niaz;
Lacaille, Jean‐Claude;
Wiebe, Shane;
Sonenberg, Nahum

Publication type:

Article

Issue Information.

Published in:: Journal of Neurochemistry, 2025, v. 169, n. 2, p. 1, doi. 10.1111/jnc.70016
Publication type:: Article

mTORC2 Regulates Actin Polymerization in Auditory Cells.

Published in:

Journal of Neurochemistry, 2025, v. 169, n. 2, p. 1, doi. 10.1111/jnc.70012

By:

Lanz, Michael;
Cortada, Maurizio;
Lu, Yu;
Levano, Soledad;
Bodmer, Daniel

Publication type:

Article

A Phase I Trial of Temsirolimus and Pemetrexed in Patients with Advanced Non-Small Cell Lung Cancer.

Published in:

Chemotherapy (0009-3157), 2016, v. 61, n. 3, p. 144, doi. 10.1159/000442147

By:

Waqar, Saiama N.;
Baggstrom, Maria Q.;
Morgensztern, Daniel;
Williams, Kristina;
Rigden, Caron;
Govindan, Ramaswamy

Publication type:

Article

姜黄素通过下调 PI3K/Akt/mTOR 信号通路蛋白表达对胃癌 MGC-803 细胞增殖和侵袭的抑制作用.

Published in:

Journal of Jilin University (Medicine Edition), 2023, v. 49, n. 2, p. 332, doi. 10.13481/j.1671-587X.20230209

By:

孙逸飞;
李迪诺;
王玉彬

Publication type:

Article

Mechanistic target of rapamycin complex 1 is involved in psoriasis and regulated by anti-TNF-α treatment.

Published in:

Experimental Dermatology, 2017, v. 26, n. 4, p. 325, doi. 10.1111/exd.13267

By:

Balato, Anna;
Lembo, Serena;
Ayala, Fabio;
Balato, Nicola;
Caiazzo, Giuseppina;
Raimondo, Annunziata;
Di Caprio, Roberta;
Monfrecola, Giuseppe

Publication type:

Article

To grow or not to grow under nutrient scarcity: Target of rapamycin-ethylene is the question.

Published in:

Frontiers in Plant Science, 2022, v. 13, p. 1, doi. 10.3389/fpls.2022.968665

By:

José García, María;
Angulo, Macarena;
Lucena, Carlos;
Pérez-Vicente, Rafael;
Javier Romera, Francisco

Publication type:

Article

Targeting PI3K/Akt/mTOR signaling in cancer.

Published in:

Frontiers in Oncology, 2014, v. 4, p. 1, doi. 10.3389/fonc.2014.00064

By:

Porta, Camillo;
Paglino, Chiara;
Mosca, Alessandra

Publication type:

Article

Methionine Promoted the Growth of Golden Pompano by Activating Intestinal Transport and TOR Signaling Pathway.

Published in:

Aquaculture Nutrition, 2025, v. 2025, p. 1, doi. 10.1155/anu/8592097

By:

Song, Zhikang;
Zhou, Yuanyuan;
Li, Yingtao;
Chen, Zhiwen;
Liu, Xingyuan;
Liu, Xinting;
Sun, Zhenzhu;
Ye, Chaoxia;
Wang, Jiting

Publication type:

Article

mTORC1 upregulation via ERK-dependent gene expression change confers intrinsic resistance to MEK inhibitors in oncogenic KRas-mutant cancer cells.

Published in:

Oncogene, 2015, v. 34, n. 45, p. 5607, doi. 10.1038/onc.2015.16

By:

Komatsu, N;
Fujita, Y;
Matsuda, M;
Aoki, K

Publication type:

Article

mTORC1/2 targeted by n-3 polyunsaturated fatty acids in the prevention of mammary tumorigenesis and tumor progression.

Published in:

Oncogene, 2014, v. 33, n. 37, p. 4548, doi. 10.1038/onc.2013.402

By:

Chen, Z;
Zhang, Y;
Jia, C;
Wang, Y;
Lai, P;
Zhou, X;
Song, Q;
Lin, Jun;
Ren, Z;
Gao, Q;
Zhao, Z;
Zheng, H;
Wan, Z;
Gao, T;
Zhao, A;
Dai, Y;
Bai, X

Publication type:

Article

Ribosomal protein S6 kinase activity controls the ribosome biogenesis transcriptional program.

Published in:

Oncogene, 2014, v. 33, n. 4, p. 474, doi. 10.1038/onc.2012.606

By:

Chauvin, C;
Koka, V;
Nouschi, A;
Mieulet, V;
Hoareau-Aveilla, C;
Dreazen, A;
Cagnard, N;
Carpentier, W;
Kiss, T;
Meyuhas, O;
Pende, M

Publication type:

Article

A tellurium-based small compound ameliorates tumor metastasis by downregulating heparanase expression.

Published in:

Journal of Cancer, 2024, v. 15, n. 16, p. 5308, doi. 10.7150/jca.96001

By:

Yuan-Hao Liu;
Li-Hsien Wu;
Wen-Jun Fan;
Shih-Han Chiu;
Pei-Hsuan Chen;
Chia C. Wang;
Che-Hsin Lee

Publication type:

Article