Title

Prostate Cancer Gene Therapy Clinical Trials.

Authors

Freytag, Svend O.; Stricker, Hans; Movsas, Benjamin; Jae Ho Kim

Abstract

Despite recent advances in early detection and treatment, prostate cancer is still the second leading cause of cancer death in men in the United States, and approximately 27,000 men will die from it this year. Better treatments are needed for aggressive forms of localized disease and hormone-refractory metastatic disease. Recently, several gene therapy strategies have generated provocative results in early-stage clinical trials, raising the possibility that gene therapy may have the potential to affect both localized and metastatic disease. Much work lies ahead. Nevertheless, for the time being, these studies provide hope that gene therapy may someday earn a place in the management of prostate cancer.Molecular Therapy (2007) 15 6, 1042–1052. doi:10.1038/sj.mt.6300162

Subjects

UNITED States; MEDICAL experimentation on humans; CANCER treatment; PROSTATE; GENE therapy; CLINICAL trials; BONE metastasis

Publication

Molecular Therapy, 2007, Vol 15, Issue 6, p1042

ISSN

1525-0016

Publication type

Academic Journal

DOI

10.1038/sj.mt.6300162