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- Title
Application of myeloid growth factors in the treatment of acute myeloid leukemia.
- Authors
Terpstra, W; Löwenberg, B
- Abstract
The current interest in the clinical use of the hematopoietic growth factors (HGF) in the treatment of patients with acute myeloid leukemia (AML) relates to the promise of reducing morbidity and improving survival through mitigating the complications of cytotoxic therapy. Another possible mode of employment of HGFs is derived from the ability of these peptides to directly stimulate leukemic cells and potentially enhance the efficacy of antileukemic therapy. Here we discuss the experimental basis and the rationale of the application of HGFs in AML and review the accumulating results from clinical studies.
- Publication
Leukemia, 1997, Vol 11, Issue 3, p315
- ISSN
0887-6924
- Publication type
Journal Article
- DOI
10.1038/sj.leu.2400561