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- Title
Myelomeningocele in an infant with intrauterine exposure to efavirenz.
- Authors
Saitoh, Akihiko; Hull, Andrew D; Franklin, Patricia; Spector, Stephen A
- Abstract
We report a case of myelomeningocele in an infant whose mother was exposed to efavirenz during the first 16 weeks of pregnancy. Although the true risk for myelomeningocele with the use of efavirenz early in pregnancy is still unknown, the findings in humans are consistent with those observed in primates and suggest that efavirenz is a potent teratogen. Thus, we suggest that efavirenz only be prescribed for women of childbearing potential when no other comparable antiretroviral options are available.
- Publication
Journal of perinatology : official journal of the California Perinatal Association, 2005, Vol 25, Issue 8, p555
- ISSN
0743-8346
- Publication type
Journal Article
- DOI
10.1038/sj.jp.7211343