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- Title
Merkel cell carcinoma: more deaths but still no pathway to blame.
- Authors
Lemos, Bianca; Nghiem, Paul
- Abstract
Merkel cell carcinoma (MCC) is a neuroendocrine skin cancer with a rising incidence (1500 U.S. cases per year) that now exceeds that of cutaneous T-cell lymphoma and a mortality (33%) exceeding that of melanoma. Despite this impact, little is known about its biology. Recent studies have shown that Ras/MAP kinase activity is absent and possibly detrimental to this cancer. This makes MCC distinct from other UV--induced skin cancers and highlights the question of what drives this malignancy.
- Publication
The Journal of investigative dermatology, 2007, Vol 127, Issue 9, p2100
- ISSN
1523-1747
- Publication type
Journal Article
- DOI
10.1038/sj.jid.5700925