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Title
Human keratinocyte Toll-like receptors promote distinct immune responses.
Authors
Miller, Lloyd S; Modlin, Robert L
Abstract
It has been well established that Toll-like receptors (TLRs) are expressed by keratinocytes and respond to their respective ligands to initiate immune responses. However, it appears that keratinocytes, via differential activation of TLRs, may play a key role in determining the type of subsequent cutaneous immune response generated against a particular pathogen.
Publication
The Journal of investigative dermatology, 2007, Vol 127, Issue 2, p262