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- Title
Effects of marked weight loss on plasma levels of adiponectin, markers of chronic subclinical inflammation and insulin resistance in morbidly obese women.
- Authors
Kopp, H-P; Krzyzanowska, K; Möhlig, M; Spranger, J; Pfeiffer, A F H; Schernthaner, G
- Abstract
Obesity is linked to the insulin resistance syndrome (IRS), type 2 diabetes (T2D) and cardiovascular disease. Markers of chronic subclinical inflammation such as high-sensitive C-reactive protein (hs-CRP) and interleukin 6 (IL-6) are closely related to insulin resistance and obesity. Recent evidence suggests that adiponectin, a protein whose circulating levels are decreased in obesity, has anti-inflammatory properties, and also appears to enhance potently insulin action and therefore appears to function as a signal produced by adipose tissue that influences whole-body glucose metabolism.
- Publication
International journal of obesity (2005), 2005, Vol 29, Issue 7, p766
- ISSN
0307-0565
- Publication type
Journal Article
- DOI
10.1038/sj.ijo.0802983