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Title
Overweight and obesity associated with a missense polymorphism in fatty acid amide hydrolase (FAAH).
Authors
Sipe, J C; Waalen, J; Gerber, A; Beutler, E
Abstract
The brain endogenous cannabinoid system modulates reward and craving pathways and consequently may affect body weight. A naturally occurring missense polymorphism in the gene encoding fatty acid amide hydrolase (FAAH), the primary enzyme for inactivation of endocannabinoids, is associated with problem drug use.
Publication
International journal of obesity (2005), 2005, Vol 29, Issue 7, p755