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- Title
Effect of pronounced weight loss on the nontraditional cardiovascular risk marker matrix metalloproteinase-9 in middle-aged morbidly obese women.
- Authors
Laimer, M; Kaser, S; Kranebitter, M; Sandhofer, A; Mühlmann, G; Schwelberger, H; Weiss, H; Patsch, J R; Ebenbichler, C F
- Abstract
Obesity is associated with increased morbidity and mortality from atherosclerotic disease. Nontraditional cardiovascular risk factors such as C-reactive protein (CRP) and interleukin-6 (IL-6) are elevated in obese subjects and weight loss is associated with an attenuation of these risk factors. Matrix metalloproteinase-9 (MMP-9) has been linked to plaque rupture, and is, thus, a candidate marker of future myocardial events. The aim of this study was to determine the influence of weight loss on MMP-9 plasma concentrations.
- Publication
International journal of obesity (2005), 2005, Vol 29, Issue 5, p498
- ISSN
0307-0565
- Publication type
Journal Article
- DOI
10.1038/sj.ijo.0802897