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- Title
Improvement of erectile function with Prelox: a randomized, double-blind, placebo-controlled, crossover trial.
- Authors
Stanislavov, R; Nikolova, V; Rohdewald, P
- Abstract
In a randomly allocated, double-blind, placebo-controlled, crossover design, 50 patients with mild to moderate erectile dysfunction (ED) were treated for 1 month with placebo or a combination of L-arginine aspartate and Pycnogenol (Prelox). Patients reported sexual function from diaries. Testosterone levels and endothelial NO synthase (e-NOS) were monitored along with routine clinical chemistry. Intake of Pycnogenol for 1 month restored erectile function to normal. Intercourse frequency doubled. e-NOS in spermatozoa and testosterone levels in blood increased significantly. Cholesterol levels and blood pressure were lowered. No unwanted effects were reported. Prelox is a promising alternative to treat mild to moderate ED.
- Publication
International journal of impotence research, 2008, Vol 20, Issue 2, p173
- ISSN
1476-5489
- Publication type
Journal Article
- DOI
10.1038/sj.ijir.3901597