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- Title
Neuroprotective and anticonvulsant effects of EGIS-8332, a non-competitive AMPA receptor antagonist, in a range of animal models.
- Authors
Gigler, G; Móricz, K; Agoston, M; Simó, A; Albert, M; Benedek, A; Kapus, G; Kertész, S; Vegh, M; Barkóczy, J; Markó, B; Szabó, G; Matucz, E; Gacsályi, I; Lévay, G; Hársing, L G, Jr; Szénási, G
- Abstract
Blockade of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptors is a good treatment option for a variety of central nervous system disorders. The present study evaluated the neuroprotective and anticonvulsant effects of EGIS-8332, a non-competitive AMPA receptor antagonist, as a potential drug candidate.
- Publication
British journal of pharmacology, 2007, Vol 152, Issue 1, p151
- ISSN
0007-1188
- Publication type
Journal Article
- DOI
10.1038/sj.bjp.0707362