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- Title
Blockade of mGluR1 receptor results in analgesia and disruption of motor and cognitive performances: effects of A-841720, a novel non-competitive mGluR1 receptor antagonist.
- Authors
El-Kouhen, O; Lehto, S G; Pan, J B; Chang, R; Baker, S J; Zhong, C; Hollingsworth, P R; Mikusa, J P; Cronin, E A; Chu, K L; McGaraughty, S P; Uchic, M E; Miller, L N; Rodell, N M; Patel, M; Bhatia, P; Mezler, M; Kolasa, T; Zheng, G Z; Fox, G B; Stewart, A O; Decker, M W; Moreland, R B; Brioni, J D; Honore, P
- Abstract
To further assess the clinical potential of the blockade of metabotropic glutamate receptors (mGluR1) for the treatment of pain.
- Publication
British journal of pharmacology, 2006, Vol 149, Issue 6, p761
- ISSN
0007-1188
- Publication type
Journal Article
- DOI
10.1038/sj.bjp.0706877