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- Title
Prostate cancer in BRCA2 germline mutation carriers is associated with poorer prognosis.
- Authors
Edwards, S M; Evans, D G R; Hope, Q; Norman, A R; Barbachano, Y; Bullock, S; Kote-Jarai, Z; Meitz, J; Falconer, A; Osin, P; Fisher, C; Guy, M; Jhavar, S G; Hall, A L; O'Brien, L T; Gehr-Swain, B N; Wilkinson, R A; Forrest, M S; Dearnaley, D P; Ardern-Jones, A T; Page, E C; Easton, D F; Eeles, R A; UK Genetic Prostate Cancer Study Collaborators and BAUS Section of Oncology
- Abstract
The germline BRCA2 mutation is associated with increased prostate cancer (PrCa) risk. We have assessed survival in young PrCa cases with a germline mutation in BRCA2 and investigated loss of heterozygosity at BRCA2 in their tumours.
- Publication
British journal of cancer, 2010, Vol 103, Issue 6, p918
- ISSN
1532-1827
- Publication type
Journal Article
- DOI
10.1038/sj.bjc.6605822