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- Title
Osteosarcoma is characterised by reduced expression of markers of osteoclastogenesis and antigen presentation compared with normal bone.
- Authors
Endo-Munoz, L; Cumming, A; Sommerville, S; Dickinson, I; Saunders, N A
- Abstract
Osteosarcoma (OS) is the most common primary bone tumour in children and adolescents. Patients who respond poorly to chemotherapy have a higher risk of metastatic disease and 5-year survival rates of only 10-20%. Therefore, identifying molecular targets that are specific for OS, or more specifically, metastatic OS, will be critical to the development of new treatment strategies to improve patient outcomes.
- Publication
British journal of cancer, 2010, Vol 103, Issue 1, p73
- ISSN
1532-1827
- Publication type
Journal Article
- DOI
10.1038/sj.bjc.6605723