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- Title
Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)-Methanandamide and JWH-015: involvement of CB2.
- Authors
Olea-Herrero, N; Vara, D; Malagarie-Cazenave, S; Díaz-Laviada, I
- Abstract
We have previously shown that cannabinoids induce growth inhibition and apoptosis in prostate cancer PC-3 cells, which express high levels of cannabinoid receptor types 1 and 2 (CB(1) and CB(2)). In this study, we investigated the role of CB(2) receptor in the anti-proliferative action of cannabinoids and the signal transduction triggered by receptor ligation.
- Publication
British journal of cancer, 2009, Vol 101, Issue 6, p940
- ISSN
1532-1827
- Publication type
Journal Article
- DOI
10.1038/sj.bjc.6605248