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- Title
Prognostic value of Dicer expression in human breast cancers and association with the mesenchymal phenotype.
- Authors
Grelier, G; Voirin, N; Ay, A-S; Cox, D G; Chabaud, S; Treilleux, I; Léon-Goddard, S; Rimokh, R; Mikaelian, I; Venoux, C; Puisieux, A; Lasset, C; Moyret-Lalle, C
- Abstract
Dicer, a ribonuclease, is the key enzyme required for the biogenesis of microRNAs and small interfering RNAs and is essential for both mammalian development and cell differentiation. Recent evidence indicates that Dicer may also be involved in tumourigenesis. However, no studies have examined the clinical significance of Dicer at both the RNA and the protein levels in breast cancer.
- Publication
British journal of cancer, 2009, Vol 101, Issue 4, p673
- ISSN
1532-1827
- Publication type
Journal Article
- DOI
10.1038/sj.bjc.6605193