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Title
Characterisation of fibronectin-mediated FAK signalling pathways in lung cancer cell migration and invasion.
Authors
Meng, X N; Jin, Y; Yu, Y; Bai, J; Liu, G Y; Zhu, J; Zhao, Y Z; Wang, Z; Chen, F; Lee, K-Y; Fu, S B
Abstract
Focal adhesion kinase (FAK) is overexpressed in a variety of cancers, such as breast, colon, prostate, ovary, and lung cancers. However, the mechanism by which extracellular matrix fibronectin stimulates lung cancer cell migration and invasion through FAK remains to be investigated.
Publication
British journal of cancer, 2009, Vol 101, Issue 2, p327