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- Title
Why are tumour blood vessels abnormal and why is it important to know?
- Authors
Nagy, J A; Chang, S-H; Dvorak, A M; Dvorak, H F
- Abstract
Tumour blood vessels differ from their normal counterparts for reasons that have received little attention. We report here that they are of at least six distinct types, we describe how each forms, and, looking forward, encourage the targeting of tumour vessel subsets that have lost their vascular endothelial growth factor-A (VEGF-A) dependency and so are likely unresponsive to anti-VEGF-A therapies.
- Publication
British journal of cancer, 2009, Vol 100, Issue 6, p865
- ISSN
1532-1827
- Publication type
Journal Article
- DOI
10.1038/sj.bjc.6604929